Generic Medicine Info
Indications and Dosage
Acute migraine attacks
Adult: As mucate: 130 mg at the onset of an attack, then 65 mg hrly thereafter as necessary. Max dose: 325 mg in 12 hr.
Porphyria; severe hypertension; severe renal and hepatic impairment; organic heart disease.
Special Precautions
CV diseases; hyperthyroidism; DM; pregnancy, lactation; angle-closure glaucoma.
Adverse Reactions
Dizziness, circulatory disturbances, rash, haematological disorders.
Drug Interactions
May antagonise hypotensive effects of adrenergic neurone blockers. Increased risk of hypertension with doxapram, oxytocin. Increased risk of ergotism with ergotamine and methysergide.
Potentially Fatal: Increased risk of hypertensive crisis with MAOIs, moclobemide. Increased risk of toxicity (severe hypertension) with bromocriptine.
Description: Isometheptene is an indirect-acting sympathomimetic and acts as a vasoconstrictor.
Store at controlled room temperature 15-30°C (59-86°F).
MIMS Class
Antimigraine Preparations / Antispasmodics
Disclaimer: This information is independently developed by MIMS based on Isometheptene from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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