Itracon

Itracon

itraconazole

Manufacturer:

Unison

Distributor:

R. Oasis
Concise Prescribing Info
Contents
Itraconazole
Indications/Uses
Aspergillosis; pulmonary & extrapulmonary blastomycosis; esophageal & oropharyngeal candidiasis; histoplasmosis, including chronic cavitary pulmonary disease & disseminated, non-meningeal disease; onychomycosis.
Dosage/Direction for Use
Aspergillosis 200 mg once-bd for at least 3 mth, may be increased to 100-400 mg/day. Treatment of blastomycosis or histoplasmosis 200 mg once daily, may be increased by 100 to max 400 mg daily. Esophageal & oropharyngeal candidiasis 100-200 mg daily for 14 days. Onychomycosis (nails only) 200 mg bd for 1 wk; this treatment is suspended for 3 wk, then resumed for 1 wk. Toenails w/ or w/o fingernail involvement 200 mg once daily for another mth.
Administration
Should be taken with food: Take immediately after a full meal.
Contraindications
Hypersensitivity to azoles. CHF or ventricular dysfunction. Consider risk-benefit: achlorhydria or hypochlorhydria.
Special Precautions
Pregnancy & lactation. Childn. Elderly.
Adverse Reactions
Hypersensitivity; CNS effects; GI disturbances.
Drug Interactions
Alprazolam, diazepam, midazolam, triazolam, antacids, anticholinergics/antispasmodics, H2-blockers, omeprazole, sucralfate, oral antidiabetic agents, astemizole or terfenadine, atorvastatin, cerivastatin, lovastatin, simvastatin, busulfan, docetaxel, vinca alkaloids, Ca-channel blockers (including felodipine, nifedipine, verapamil), carbamazepine, phenobarb, phenytoin, cisapride, cyclosporine or tacrolimus, didanosine, digoxin, dofetilide or quinidine, INH or rifampin, macrolides (including clarithromycin or erythromycin), pimozide, warfarin.
MIMS Class
Antifungals
ATC Classification
J02AC02 - itraconazole ; Belongs to the class of triazole derivatives. Used in the systemic treatment of mycotic infections.
Presentation/Packing
Form
Itracon cap 100 mg
Packing/Price
25 × 4's
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