Bromhexine HCl, Glyceryl Guaiacolate.
Each 5-mL syrup contains Bromhexine Hydrochloride 10 mg and Glyceryl Guaiacolate 50 mg.
Konidin Mucolytic Expectorant Syrup is a combination of mucolytic and expectorant. Bromhexine HCl and Glyceryl guaiacolate work directly on mucous secreting cells in respiratory tract by breaking the acid mucoply-saccharide fibres. The breakdown of mucoply-saccharide fibres makes the sputum thinner and less viscid and therefore easily removed by coughing.
Pharmacokinetics: Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and about 85-90% of the dose is excreted in the urine mainly as metabolites. Bromhexine is highly bound to plasma proteins.
Glyceryl guaiacolate is absorbed from the gastrointestinal tract. It is metabolized and excreted in the urine.
Relief of productive cough symptoms and all forms of upper and lower respiratory tract conditions associated with retention of viscid mucous secretion.
Adults and Children >10 years: 1 tsp (5 mL) 3 times daily. Children 5-10 years: ½ tsp (2.5 mL) 3 times daily.
Warning should be given to patients with peptic ulcer. It may cause gastrointestinal discomfort and increase transaminase level.
Use in pregnancy: Special precaution is also given to pregnancy women especially the first
Use in pregnancy: Special precautions should be given to pregnant women especially during the 1st trimester of pregnancy.
Gastrointestinal discomfort eg, nausea, vomiting diarrhea, peptic ulcer and headache. It has been reported that it may cause excessive sweat, headache and vertigo.
R05CB10 - combinations ; Belongs to the class of mucolytics. Used in the treatment of wet cough.