Kremil-S/Kremil-S Reformulated

Kremil-S/Kremil-S Reformulated

Manufacturer:

United Pharma

Distributor:

Success and Success
Full Prescribing Info
Contents
Kremil-S: AHMC Type F-MA 11, dimethylpolysiloxane, dicyclomine HCl.
Kremil-S Reformulated: Aluminum hydroxide, magnesium hydroxide, simethicone.
Description
Kremil-S: Each tablet contains AHMC Type F-MA 11 325 mg, dimethylpolysiloxane 10 mg and dicyclomine HCl 2.5 mg.
Kremil-S Reformulated: Each tablet contains aluminum hydroxide 178 mg, magnesium hydroxide 233 mg and simethicone 30 mg.
Action
Kremil-S is an antipeptic ulcer preparation with antacid, antiflatulent and spasmolytic effects. Kremil-S neutralizes acid faster, adjusts the gastric pH to the ideal range of 3-5 and maintains it longer than any other antacid. It corrects the problem of excessive gastrointestinal gas experienced by many patients; breaks up the mucus that envelops gas bubbles so that these are immediately released and prevented from producing abdominal discomfort. It relaxes the hyperactive smooth muscles of the gastrointestinal tract to check hypermotility or spasms that aggravate peptic ulcer pains.
Kremil-S promotes the healing of ulcer.
Indications/Uses
For prompt and prolonged treatment of peptic ulcer and relief of hyperacidity, gastric hypermotility, spastic and irritable colon, flatulent dyspepsia, gastritis, heartburn, duodenitis, esophagitis, hiatus hernia, dietary indiscretion, alcoholic intoxication and postoperative abdominal pains.
As adjunct to H2 blockers or proton pump inhibitors for the rapid relief of ulcer symptoms.
Dosage/Direction for Use
For peptic ulcer and gastritis, 2-4 tabs every 4 hrs or as prescribed by the physician.
For symptoms of gastric hyperacidity (heartburn, acid indigestions, belching, gas and epigastric pain), 1-2 tabs after meals or as needed.
The tablets may be chewed or swallowed directly.
Contraindications
Patients with closed-angle glaucoma or those with narrow-angle between the iris and the cornea since it may raise intraocular pressure.
Do not use in patients suffering from paralytic ileus or pyloric stenosis where its use may lead to obstruction.
Special Precautions
Use with caution in patients with coronary insufficiency, cardiac failure or prostatic enlargement. Tachycardia may result from vagal inhibition or induce angina of effort in patients with coronary heart disease.
Aluminum hydroxide mixture interfere with or reduce the absorption of any prescription drug containing any form of tetracycline. Magnesium salts, in the presence of renal impairment, may cause CNS depression. In highly susceptible individuals, the antispasmodic component (dicycloverine) may cause dryness of the mouth, dizziness and blurred vision. Occasionally, some patients may experience fatigue, nausea, headache and dysuria.
Kremil-S/Kremil-S Reformulated should not be used in patients suffering from paralytic ileus or pyloric stenosis where its use may lead to obstruction. It is contraindicated in patients with closed-angle glaucoma or in patients with a narrow angle between the iris and the cornea, since it may raise intra-ocular pressure.
Adverse Reactions
Magnesium salts, in the presence of renal impairment, may cause CNS depression. In highly susceptible individuals, the antispasmodic component (dicyclomine HCl) may cause dryness of the mouth, dizziness and blurred vision. Occasionally, some patients may experience fatigue, nausea, headache and dysuria.
Drug Interactions
Aluminum hydroxide mixtures interfere with or reduce the absorption of any prescription antibiotic drug containing any form of tetracycline.
ATC Classification
A02AF01 - magaldrate and antiflatulents ; Belongs to the class of antacids with antiflatulents.
A02AX - Antacids, other combinations ; Used in the treatment of acid-related disorders.
Presentation/Packing
Kremil-S: Tab 5 x 20's.
Kremil-S Reformulated: Tab 25 x 4's.
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