Levotab

Levotab

levofloxacin

Manufacturer:

Pacific Pharma (Korea)

Distributor:

AA Medical
Concise Prescribing Info
Contents
Levofloxacin
Indications/Uses
Susceptible infections, eg, acute exacerbations of chronic bronchitis; community acquired pneumonia; sinusitis; complicated UTI & acute pyelonephritis; uncomplicated UTI in women; uncomplicated & complicated skin & soft tissue infections; intra-abdominal infections.
Dosage/Direction for Use
Usual dose: 250 or 500 mg once daily or bd continued for a min 48-72 hr after commencement of therapy. Bacterial bronchitis exacerbations 500 mg once daily for 5-10 days. Community acquired pneumonia 500 mg once daily, or bd for 10-14 days. Sinusitis 500 mg once daily for 10-14 days. Complicated UTI & acute pyelonephritis 250 mg once daily for 10 days. Uncomplicated UTI in women 250 mg once daily for 3 days. Uncomplicated skin & soft tissue infections 250-500 mg once daily for 7-10 days. Complicated skin & soft tissue infections 500 mg once daily for 10-14 days. Intra-abdominal infections 500 mg once daily in combination w/ an antibiotic w/ anaerobic coverage for 10-14 days. Presence of bacteraemia or septicaemia in previously mentioned infections 500 mg bd for 10-14 days. Renal impairment CrCl 20-50 mL/min 250 or 500 mg once-daily dose: Initially, single normal dose, reduced to ½ the dose once daily. 500 mg bd dose: Initially 500 mg, then 250 mg 12 hrly. 10-19 mL/min 250 mg once-daily dose: Initially, single normal dose, reduced to 125 mg 48 hrly. 500 mg once-daily dose: Initially, a single normal dose, reduced to 125 mg 24 hrly. 500 mg bd dose: Initially, 500 mg, reduced to 125 mg 12 hrly. <10 mL/min or patients on haemodialysis or continuous ambulatory peritoneal dialysis 250 mg once daily dose: Initially, a single normal dose, reduced to 125 mg 48 hrly. 500 mg once-daily dose: Initially, a single normal dose, reduced to 125 mg 24 hrly. 500 mg bd dose: Initially 500 mg, reduced to 125 mg 24 hrly.
Administration
May be taken with or without food: Swallow whole, do not crush.
Contraindications
Hypersensitivity to levofloxacin or other quinolones. Epilepsy. History of tendon disorders associated w/ fluoroquinolones. Pregnancy & lactation. Childn & adolescents (<18 yr).
Special Precautions
Seizure-prone patients eg, w/ pre-existing CNS lesions. Concurrent use w/ fenbufen or NSAIDs, or cerebral seizure threshold lowering agents eg, theophylline. May give false -ve results in the bacteriological diagnosis of TB. Exposure to UV light. May alter the ability to drive or operate machinery. Not for patients <18 yr.
Drug Interactions
Reduced absorption w/ Fe salts, sucralfate, & Mg- or Al-containing antacids; do not take 2 hr before or after levofloxacin administration. May interfere w/ the clearance of theophylline, fenbufen or seizure threshold lowering NSAIDS.
MIMS Class
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Presentation/Packing
Form
Levotab FC caplet 250 mg
Packing/Price
1's
Form
Levotab FC caplet 500 mg
Packing/Price
1's
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