Levonorgestrel should not be used during pregnancy. If a pregnancy occurs, levonorgestrel treatment should be stopped immediately.
Extensive epidemiological studies have revealed neither an increased risk of birth defects in children from women who used oral contraceptives prior to pregnancy, nor a teratogenic effect when oral contraceptives were taken inadvertently during early pregnancy. To date relevant epidemiological data with respect to use of progestogen-only contraceptives during pregnancy are not available.
Similar to other progestogen-only contraceptives, levonorgestrel does not influence the production or the quality of breast milk. However, a small amount of progestogen is excreted with the milk. The amount of levonorgestrel and metabolites excreted in the milk is about 0.14% of the daily-administered dose, but no adverse effects on infant growth and development have been reported.