If taken concomitantly, it is likely that food and beverages (including mineral water), calcium supplements, antacids, and some oral medicinal products will interfere with absorption of alendronate. Therefore, patients must wait at least 30 min after taking alendronate before taking any other oral medicinal product (see Pharmacokinetics under Actions and Dosage & Administration).
No other interactions with medicinal products of clinical significance are anticipated. A number of patients in the clinical trials received oestrogen (intravaginal, transdermal or oral) while taking alendronate. No adverse experiences to the concomitant use were identified.
Although, specific interaction studies were not performed, in clinical studies, alendronate was used concomitantly with a wide range of commonly prescribed medicinal products without evidence of clinical adverse interactions.
Incompatibilities: Not applicable.