Mebhydrolin


Concise Prescribing Info
Indications/Uses
Allergic conditions.
Dosage/Direction for Use
Adult : PO 100-300 mg/day.
Dosage Details
Oral
Allergic conditions
Adult: 100-300 mg/day.
Child: <2 yr: 50-100 mg/day; 2-5 yr: 50-150 mg/day; 5-10 yr: 100-200 mg/day; >10 yr: 100-300 mg/day.
Administration
Should be taken with food. Take during or shortly after meals.
Contraindications
Premature infants and neonates. Acute asthmatic attack.
Special Precautions
Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery.
Adverse Reactions
CNS depression; paradoxical stimulation (high doses, children or elderly); headache, psychomotor impairment; dry mouth, thickened respiratory tract secretions, blurred vision; urinary difficulty or retention, constipation, increased gastric reflux; nausea, vomiting, diarrhoea, epigastric pain. Rarely, blood disorders. Convulsions, sweating, myalgia, paraesthesias, extrapyramidal effects, tremor, sleep disturbances, depression, confusion, tinnitus, hypotension, hair loss.
Potentially Fatal: Anaphylaxis.
Drug Interactions
Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.
Lab Interference
May interfere with allergy skin testing by suppressing cutaneous histamine response to allergen extracts.
Action
Description: Mebhydrolin is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.
Storage
Store below 25°C.
Disclaimer: This information is independently developed by MIMS based on Mebhydrolin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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