Medrogestone


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Menopausal HRT; Menstrual disorders 5-10 mg/day in a cyclical regimen.
Dosage Details
Oral
Menopausal hormone replacement therapy, Menstrual disorders
Adult: 5-10 mg daily in a cyclical regimen.
Contraindications
Undiagnosed vaginal bleeding, severe hepatic impairment, arterial disease, porphyria, pregnancy testing, pregnancy.
Special Precautions
CV or renal impairment, DM, asthma, epilepsy, migraines, history of depression, conditions which may be aggravated by fluid retention. Lactation.
Adverse Reactions
GI disturbances, changes in appetite or weight, oedema, acne, chloasma, breast changes, hirsutism, headache, changes in serum lipids.
Drug Interactions
Enzyme-inducing drugs may enhance clearance. May inhibit ciclosporin metabolism. Antidiabetic dosage may need to be adjusted.
Action
Description: Medrogestone is a progestogen related to progesterone. It is used in hormone replacement therapy and menstrual disorders and has been used in the past for breast cancer, cancer of the endometrium and prostatic hyperplasia.
Disclaimer: This information is independently developed by MIMS based on Medrogestone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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