Etoricoxib is administered orally with or without food.
Arthritis: Osteoarthritis: 60 mg once daily.
Rheumatoid Arthritis: 90 mg once daily.
Acute Gouty Arthritis: 120 mg once daily.
Etoricoxib 120 mg should be used only for the acute symptomatic period.
Analgesia: Acute pain: The recommended dose is 120 mg once daily.
Chronic Musculoskeletal Pain: 60 mg once daily.
No dosage adjustment is necessary for the elderly.
Hepatic insufficiency: Mild hepatic insufficiency: a dose of 60 mg once daily should not be exceeded. Moderate hepatic insufficiency (Child-Pugh score 7-9) a dose of 60 mg every alternate day should not be exceeded.
Severe hepatic insufficiency (Child-Pugh score >9): No data available.
Renal insufficiency: Not recommended in advanced renal disease (creatinine clearance <30 ml/min).
No dosage adjustment is necessary for patients with lesser degrees of renal insufficiency.