Miltefosine


Generic Medicine Info
Indications and Dosage
Oral
Visceral leishmaniasis
Adult: 100-150 mg daily for 28 days.

Topical/Cutaneous
Mycosis fungoides, Skin metastases of breast cancer
Adult: 6% solution applied 1-2 times daily.
Contraindications
Pregnancy, lactation, concurrent radiation therapy.
Special Precautions
Metastases grown over breast implants.
Adverse Reactions
Oral: leukocytosis; thrombocytosis; GI irritation, nausea, vomiting, diarrhoea, constipation; ocular, hepatic, renal toxicity. Topical: pruritis; erythema; scaling; xerosis; tightness of the skin; dermatitis; pain; ulceration; necrosis.
Action
Description: Miltefosine is a phospholipid derivative thought to work by disrupting cell-membrane function.
MIMS Class
Cytotoxic Chemotherapy / Other Antiprotozoal Agents
Disclaimer: This information is independently developed by MIMS based on Miltefosine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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