Prevention of post-partum hemorrhage: 600 mcg orally administrated immediately after the delivery of the baby and confirmation that all the features have been delivered (in case of multiple births).
Treatment of post-partum hemorrhage: 800 mcg sublingually or 1000 mcg administrated rectally significantly reduces the need for additional interventions.
Treatment of incomplete abortion and missed miscarriage in the first trimester: 800 mcg administered vaginally or sublingually and repeated after 24 hours. (Healthcare provider is advised to offer all women receiving medical management of miscarriage pain relief, antibiotics and antiemetics as needed).
Treatment of duodenal ulcer, gastric ulcer and NSAID induced peptic ulcer: 800 mcg orally taken in two or four divided doses after breakfast and/or main meal and at bedtime. In most patients, ulcer will be healed in four weeks but treatment may be continued for up to eight weeks if required. If the ulcer relapses further, treatment courses may be given.