Neostigmine - oral

Patient Medicine Information
Why do I need this medicine?
Neostigmine is used to improve muscle strength. This medicine is used in the treatment of myasthenia gravis (muscle weakness disorder).

This medicine may also be used in the management of paralytic ileus (a condition where the bowel does not work properly) and postoperative urinary retention (inability to empty the bladder and urinate).

Neostigmine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Neostigmine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine may be taken with or without meals. Consider taking the larger portion of your daily dose during the time where in you are prone to experience tiredness e.g. mealtime, afternoon. Try to take it at the same time each day.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have any of these conditions:

- bowel or intestine obstruction (blockage of the intestines)
- urinary tract (bladder or urethra) disorder
- peritonitis (inflammation of the lining in the abdomen)
as this medicine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have:

- asthma
- heart disease
- epilepsy (fits or seizure)
- hyperthyroidism (thyroid gland disorder)
- Parkinson's disease (disorder that affects movement, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking)
- kidney disease
- stomach ulcer
- undergone recent intestine or bladder surgery
- irritability of the vagus nerve which causes excessive contractions of your bowels

Let your doctor know if you are pregnant or breastfeeding.
What side effects could I experience?
Neostigmine may cause any of the following side effects: nausea, vomiting, increased salivation, abdominal pain, diarrhoea.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor if you are taking any of these:

- medicines for bacterial infections e.g. clindamycin, colistin
- medicines for arrhythmia (irregular heartbeat) e.g. procainamide, propafenone, quinidine
- medicines for mood disorder e.g. lithium

This list does not include all medicines that may interact with Neostigmine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on neostigmine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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