Palonosetron - oral

Patient Medicine Information
Why do I need this medicine?
Palonosetron is used to prevent nausea and vomiting associated with cancer chemotherapy (cancer treatment).
How do I take this medicine?
Take Palonosetron exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take Palonosetron with or without food.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember.

DO NOT double a dose under any circumstances.
What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:

  • history of constipation
  • blocked bowel
  • heart disease e.g. abnormal heart rhythm
  • abnormal levels of potassium, sodium, magnesium, calcium in the blood
Let your doctor know if you are pregnant or breastfeeding.
What side effects could I experience?
Palonosetron may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects may include any of the following: headache, diarrhea, tiredness and constipation.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • confusion and hallucinations (seeing, hearing or feeling things that are not existent)
  • restlessness, lack of coordination, muscle stiffness, increased body temperature, fast heartbeat
  • seizures
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines used to treat depression e.g. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine
  • medicines for moderate to severe pain e.g. tramadol, fentanyl
This list does not include all medicines that may interact with Palonosetron.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on palonosetron - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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