Generic Medicine Info
Indications and Dosage
Pancreatic insufficiency
Adult: Dose is adjusted according to dosage form and patient's needs. Usual dose with each meal: 5,000-56,000 units of lipase activity (with varying proportions of protease and amylase activity, depending on the preparation).
Child: Dose dependant upon dosage form and patient's needs. Children with cystic fibrosis max dose: 10,000 units lipase/kg/day.
Acute pancreatitis or acute exacerbation of chronic pancreatic disease.
Special Precautions
Avoid high doses in patients with cystic fibrosis. Maintain adequate hydration. Some products contain pork protein. Inactivated by heat; do not mix with hot food or liquids. May irritate oral mucosa; should not be held in mouth. Pregnancy and lactation.
Adverse Reactions
GI effects e.g. abdominal discomfort, nausea and vomiting. Buccal and perianal irritation, particularly in infants. Colonic strictures may occur, mainly in children with cystic fibrosis receiving high doses of pancreatin preparations. Hyperuricaemia and hyperuricosuria may occur.
May lead to laxative effect; treatment: supportive.
Drug Interactions
May impair the oral absorption of folic acid when taken together; antagonises hypoglycaemic effect of acarbose.
Description: Pancreatin are pancreatic enzymes which hydrolyse fats to glycerol and fatty acids, break down protein into peptides, proteoses and derived substances, and convert starch into dextrins and sugars.
Store at 15-30°C. Protect from humidity.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Pancreatin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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