Overdosage can produce hypoglycemia. Mild symptoms without loss of consciousness can be treated with oral glucose. Severe hypoglycemic reactions eg, coma, seizures require medical emergencies. Hypoglycemic coma should be treated with rapid IV infusion of concentrated glucose (50%) solution. This should be followed by continuous infusion of dilute glucose (10%) to maintain glucose levels >100 mg/dL. Patients should be closely monitored for 24-48 hrs as hypoglycemia may recur.