Pethidine is used for the relief of moderate to severe pain.
Take Pethidine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Oral solution should be taken in one half glass of water. Try to take it at the same time each day.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you have lung failure (e.g. blocked airways, damaged lung tissues, asthma) as this medicine may not be suitable for you.
Do not take Pethidine if you are currently taking or have taken a medicine to treat depression known as monoamine oxidase inhibitor (MAOI) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days. Please see the section “Can I take this with other medicines?” below for more information.
Inform your doctor if you have the following conditions:
- delirium tremens (tremors, hallucination and disorientation caused by withdrawal from alcohol)
- drug abuse or history of drug abuse
- alcohol dependence
- head injury
- liver disease
- phaeochromocytoma (tumour of the adrenal gland)
- kidney disease
- enlargement of the prostate
- seizure (fits)
- thyroid disorder e.g. low activity of thyroid glands
- bile disorder e.g. inflammation of the pancreas
- fast heartbeat
- blood disorder e.g. sickle cell anaemia (red blood cell disorder)
- mental illnesses
Let your doctor know if you are pregnant or breastfeeding.
Do not give this medicine to children especially on infants unless instructed to do so by the doctor.
Pethidine may cause dizziness or drowsiness. If affected, do not drive or take part in any activity in which you need to be alert.
You may also feel dizzy when getting up from a sitting or lying down position, especially if you are taking this medicine for the very first time. This is common and should improve gradually as you get used to this medicine. It will help if you get up slowly from a sitting or lying down position. If you are taking this medicine for the very first time, take the first dose of Pethidine at bedtime to minimise dizziness.
Other side effects may include any of the following: nausea, vomiting, headache, palpitations, tiredness. difficulty urinating, sweating, dry mouth, constipation, and rash.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- unusual changes in mood or behaviour (being too depressed, agitated, or having alternating periods of feeling happy and unhappy)
- hallucinations (seeing, hearing or feeling things that are not existent)
- irregular heartbeat
- muscle twitching
- seizure (fits)
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Do not take Pethidine if you are currently taking or have taken a medicine to treat depression known as monoamine oxidase inhibitor (MAOI) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for viral infections e.g. ritonavir, aciclovir
- medicines for bacterial infections e.g. linezolid
- medicines for TB (lung infection known as tuberculosis) e.g. isoniazid
- medicines for epilepsy (fits or seizure) e.g. phenytoin, phenobarbital, carbamazepine
- medicines for mood disorders e.g. chlorpromazine, prochlorperazine
- medicines for stomach ulcer e.g. cimetidine
This list does not include all medicines that may interact with Pethidine.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.