Pilsicainide hydrochloride


Concise Prescribing Info
Indications/Uses
Atrial fibrillation.
Dosage/Direction for Use
Adult : PO 100-150 mg as a single dose.
Dosage Details
Oral
Atrial fibrillation
Adult: 100-150 mg as a single dose.
Contraindications
Control of asymptomatic arrhythmias in patients with history of MI.
Special Precautions
Patients with compromised left ventricular function. Electrolyte imbalances should be corrected prior to starting therapy. Hepatic impairment.
Adverse Reactions
Dizziness, visual disturbances and lightheadedness. Nausea, vomiting, headache, tremor, peripheral neuropathy, ataxia and paraesthesia. Hallucinations, amnesia, confusion, depression, dyskinesias and convulsions may also occur.
Potentially Fatal: MI.
Drug Interactions
Increased risk of cardiac arrhythmias when used with other anti-arrhythmic drugs.
Action
Description: Pilsicainide is a class Ic antiarrhythmic with sodium channel blocking action. It has a depressant effect on intra-atrial conduction and a prolonging effect on the atrial effective refractory period.
Pharmacokinetics:
Absorption: Rapidly absorbed from the GI tract.
Disclaimer: This information is independently developed by MIMS based on Pilsicainide hydrochloride from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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