Rimexolone


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : Ophth Post-op ocular inflammation As 1% susp: Apply 1-2 drops 4 times/day for 2 wk, starting 24 hr post-op. Anterior uveitis As 1% susp: Apply 1-2 drops hrly during waking hr for the 1st wk, followed by 2 hrly for 2nd wk, 4 times/day for 3rd wk, twice daily during the 1st 4 days of 4th wk and then once daily during the last 3 days of the 4th wk. Ocular inflammationAs 1% susp: Apply 1 drop ≥4 times/day for not >4 wk.
Dosage Details
Ophthalmic
Ocular inflammation
Adult: As 1% suspension: Apply 1 drop into the conjunctival sac of the affected eye ≥4 times daily. Treatment duration should not be >4 wk.

Ophthalmic
Anterior uveitis
Adult: As 1% suspension: Apply 1-2 drops into the conjunctival sac of the affected eye during waking hr, hourly for the 1st wk, every 2 hrly during the 2nd wk, 4 times daily during the 3rd wk, bid during the 1st 4 days of 4th wk and then once daily during the last 3 days of the 4th wk.

Ophthalmic
Postoperative ocular inflammation
Adult: Apply 1-2 drops into the conjunctival sac of the affected eye 4 times daily for 2 wk, starting 24 hr after surgery.
Contraindications
Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, viral diseases of the cornea and conjunctiva, mycobacterial, fungal or amoebic infection of the eye; acute purulent untreated infections which may be masked or enhanced by the use of the steroid; undiagnosed red eye.
Special Precautions
Temporary, blurred vision may occur immediately after admin, do not drive or operate machinery if affected. Re-evaluate if sign and symptoms do not improve after 2 days and monitor intraocular pressure if used ≥10 days. For ophthalmic use only, not to be used as inj. Shake well before use. Pregnancy.
Adverse Reactions
Blurring of vision, discharge, eye pain and discomfort, foreign body sensation, hyperaemia, pruritus, thinning of the cornea and sclera. Prolonged use may result in ocular hypertension, glaucoma, optic nerve damage, visual acuity and visual fields defects, formation of posterior subcapsular cataract and secondary ocular infections.
Overdosage
In topical overdose, rinse eye with lukewarm water.
Action
Description: Rimexolone is a topical corticosteroid used to treat inflammatory eye disorders.
Pharmacokinetics:
Metabolism: Undergoes extensive hepatic metabolism. Half-life: 1-2 hr.
Excretion: Excretion via faeces.
Storage
Store upright between 36-77°F (2-25°C), do not freeze.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Rimexolone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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