Sodium hyaluronate


Generic Medicine Info
Indications and Dosage
Intra-articular
Osteoarthritis of the knee
Adult: 20-25 mg once weekly for 5 weeks or up to 30 mg once weekly for 3-4 weeks. Not to repeat treatment course within 6 months for any individual joint.

Ophthalmic
Surgical aid in the anterior segment during cataract extraction and intraocular lens implantation
Adult: Apply a sufficient quantity into the eye, as required.

Topical/Cutaneous
Skin ulcers and wounds
Adult: As cream or gel: Apply a thin layer onto clean and disinfected wound/ulcer bid or tid.
Contraindications
Hypersensitivity to sodium hyaluronate or avian proteins.
Special Precautions
Monitor intraocular pressure. Pregnancy.
Adverse Reactions
Ophthalmic: Transient rise in intraocular pressure. Intra-articular inj: Pain and inflammation at inj site. Hypersensitivity; anaphylaxis; hypotensive crisis.
Action
Description: Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
Pharmacokinetics:
Distribution: Widely distributed in body tissues and intracellular fluids.
Excretion: Ophthalmic, via Canal of Schlemm.
Storage
Store at 2-25°C.
MIMS Class
Emollients, Cleansers & Skin Protectives / Other Drugs Acting on Musculo-Skeletal System / Other Eye Preparations
Disclaimer: This information is independently developed by MIMS based on Sodium hyaluronate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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