Somatrem


Concise Prescribing Info
Dosage Details
Parenteral
Growth hormone deficiency
Child: 4 units 3 times/wk. May be given via SC or IM inj.
Contraindications
Active neoplasms or intracranial lesions; closed epiphyses. Pregnancy. Proliferative or preproliferative diabetic retinopathy. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment.
Special Precautions
DM (adjustment of antidiabetic therapy may be necessary); acute catabolic states (severe burns or critically ill). Lactation. Discontinue treatment if there is evidence of tumour growth. Monitoring during therapy is recommended in patients with scoliosis due to risk of progression of scoliosis that can occur with rapid growth. Hypothyroidism may develop during therapy causing suboptimal response.
Adverse Reactions
Redness, itching, lumps or lipoatrophy at inj site. Headache, muscle and joint pain, benign intracranial hypertension. May increase risk of ear disorders in patients with Turner's syndrome.
Drug Interactions
Growth-promoting effect may be inhibited by corticosteroids.
Action
Description: Somatrem is an analogue of somatropin containing an additional (methionyl) amino acid residue. It is commonly used in children with open epiphyses for the treatment of short stature due to deficiency of growth hormone. May also be used in adults with confirmed growth hormone deficiency or management of wasting or cachexia associated with AIDS.
Disclaimer: This information is independently developed by MIMS based on Somatrem from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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