Speeda Dosage/Direction for Use

vaccine, rabies


Liaoning Chengda Biotechnology


Shein Tet
Full Prescribing Info
Dosage/Direction for Use
IM Administration: 0.5 mL dose of vaccine shall be injected IM in the deltoid in adults and in the arterio-lateral region of the thigh in young children. Do not inject in the gluteal region.
Intradermal Administration: 0.1 mL dose of vaccine (per site) shall be injected in deltoid.
Pre-exposure Schedule: 3 injections on Day 0, 7 and 28. The injection schedule on Day 28 may be administered on Day 21.
Post-exposure Schedule: Auxiliary Therapy: The treatment of wound is very important and must be performed promptly after the bite. It is recommended firstly to wash the wound with large quantity of water and soap and with detergent and then apply 70% alcohol, tincture of iodine or 0.1% quaternary ammonium solution (provided no soap remains as the 2 products neutralize each other). Curative vaccination must be administered under the medical supervision and only in babies treatment centre.
Vaccination of Non-immunized Subjects: IM schedule (standard IM regimen: ESSEN): 5 injections (0.5 mL) will be given on Day 0, 3, 7, 14 and 28. Intradermal schedule (Modified TRC-ID regimen, 2-2-2-0-2): One dose of vaccine in a volume of 0.1 mL is given intradermally at 2 different sites usually the left and right upper arm on Days 0, 3, 7 and 28.
In the case of type III, anti-rabies immunoglobulin should be administered as well on Day 0. The anti-rabies immunoglobulin (20 IU/kg) of specific human rabies immune globulin or 40 IU/kg of purified rabies serum of equine origin should be used as local wound soakage injection as much as possible with the rest part for muscle injection. The rabies vaccine should be administered in different injection site.
Vaccination of subjects already fully Immunized against Rabies: If vaccine administered in less than 6 months of exposure (cell culture rabies vaccine): Then 1 injection on D0 is recommended.
If vaccine administered in more than 6 months of exposure (cell culture rabies vaccine): Then 2 injections on D0, D3 are recommended.
Reconstitution: To reconstitute the vaccine, introduce the diluent 0.5 mL into the vial of powder and shake thoroughly until the powder is dissolved completely. The solution should be homogenous, clear and free of any particles. Withdraw the solution in a syringe.
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