IV injection is prohibited.
The vaccine and anti-rabies immunoglobulin must not be administered with the same syringe and in the same injection site.
Before use, please carefully check package, label, appearance and the validity period.
After reconstitution, the freeze-dried rabies vaccine should be administered as soon as possible.
Special Precautions for the Intradermal Route: It is essential that intradermal administration of this vaccine be carried out only by medical staff trained in this technique in order to ensure that the vaccine is delivered intradermally and not subcutaneously.
In the event that a dose of vaccine is inadvertently given SC or IM, a new dose should be administered intradermally immediately.
For the intradermal route a sterile syringe with fixed needle (insulin type) is preferred.
A sterile needle and syringe must be used to withdraw and administer each dose of vaccine for each patient to avoid cross infection. Correct intradermal injection should result in a raised papule with a "peau d'orange" (orange peel) appearance. If the vaccine has been injected too deeply and a papule is not seen, the needle should be withdrawn and re-inserted nearby.
This vaccine does not contain a preservative therefore, great care must be taken to avoid contamination of reconstituted vaccine.
Any reconstituted vaccine should be used as soon as possible. It must be stored in the refrigerator at +2°C and +8°C and used within 8 hrs after reconstitution or discarded.
The intradermal route must not be used in the following instances: Individuals receiving long-term corticosteroid or other immunosuppressive therapy or chloroquine; immunocompromised individuals.