The recommended daily dose of tamoxifen is 20mg daily. Doses of 30mg or 40mg daily have been used in patients with advanced disease.
No modification to the dosage need be made in the elderly or in patients with renal or hepatic dysfunction.
No dosage regimen has been determined for children.
The maximum daily dose of tamoxifen is 40mg. An objective response is usually observed within four to ten weeks of therapy, but may take several months in patients with bone metastases.
Tablets are to be taken with some fluid.
If taking of more than one Tamoxifen "Ebewe" tablet is necessary they can be taken once or twice a day.
Duration of treatment depends on severity of the disease, commonly long-term treatment rsp. until relapse occurs.