Trandolapril + verapamil - oral

Trandolapril and Verapamil are combined together in this medicine.

This medicine helps to keep your blood pressure under control. It relaxes your blood vessels and this helps to lower your blood pressure.

Take Trandolapril + Verapamil exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal. Try to take it at the same time each day.

Trandolapril + Verapamil must be taken regularly for it to be effective. Continue taking this medicine even when you feel better/well. Do not stop taking it unless instructed by the doctor.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

Alert your doctor if you have the following conditions:

• heart disease e.g. heart failure, slow heart rate, irregular heartbeat, heart conduction problem 
• low blood pressure

as Trandolapril + Verapamil may not be suitable for you.

Do not take Trandolapril + Verapamil if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Trandolapril + Verapamil may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.

Do not breastfeed while you are being treated with this medicine.

Do not take Trandolapril with aliskiren (medicine used to treat hypertension) if you have diabetes.

Do not take this medicine if you are currently taking or have taken sacubitril (medicine to help keep high blood pressure in control) in the last 36 hours.

Inform your doctor if you have the following conditions:

• heart problems such as narrowing of the valves of the heart 
• kidney disease
• liver disease
• immune system diseases affecting collagen

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Trandolapril + Verapamil.

For as long as you are taking Trandolapril + Verapamil, you may need to monitor your blood pressure and heart rate regularly to check your body’s response to the medicine. Routine tests for your kidney function and electrolyte level may also be done. Your doctor will advise you about how often you need to have these tests.

What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help lower your blood pressure and improve your overall health. Engage in physical activity (e.g. walking) at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to kick your smoking habit.

Try to keep stress levels under control as stress will cause your blood pressure to go up.

Trandolapril + Verapamil may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects may include any of the following: headache, cough, constipation, nausea and stomach pain.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

• swelling of hands, legs, face, or mouth
• fast or irregular heartbeat 
• rashes with skin peeling or blisters
• yellowing of the eyes or skin

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Inform your doctor and pharmacist if you are taking any of these medicines:

• medicine for mood disorders e.g. lithium
• medicines for pain and inflammation e.g. aspirin, ibuprofen
• medicines for diabetes e.g. insulin, metformin
• potassium supplements (either as a medicine or as a salt substitute)
• other medicines for high blood pressure or heart disease e.g. atenolol, propranolol, prazosin, digoxin, amiodarone 
• cholesterol-lowering medicine e.g. simvastatin, lovastatin
• medicines for HIV infection e.g. ritonavir
• antibiotics e.g. erythromycin, clarithromycin
• medicine for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin 
• medicine used in organ transplant or certain immune disorders e.g. ciclosporin
• medicines for tuberculosis e.g. rifampicin 

This list does not include all medicines that may interact with Trandolapril + Verapamil.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.

Avoid alcohol.

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.