As with other cephalosporins, anaphylactic shock cannot be ruled out even if a thorough patient history is taken. Anaphylactic shock requires immediate countermeasures, eg I.V. epinephrine (adrenaline) followed by a glucocorticoid.
In rare cases, shadows suggesting sludge have been detected by sonograms of the gallbladder. This condition was reversible on discontinuation or completion of TRAXONE Inj. therapy. Even if such findings are associated with pain, conservative, nonsurgical management is recommended. In vitro studies have shown that ceftriaxone, like some other cephalosporins, can displace bilirubin from serum albumin. Caution should be exercised when considering TRAXONE Inj. for hyperbilirubinemic neonates especially prematures. During prolonged treatment, the blood cell count should be checked regularly.