Trifluoperazine is used to treat and relieve symptoms common in schizophrenia (brain disorder referring to a disruption of usual balance of emotions and thinking) and paranoia such as distorted thinking and emotional instability.
It is also used in the short-term treatment of anxiety, agitation and dangerously impulsive behaviour.
Trifluoperazine may also be used for other medical conditions, such as nausea and vomiting.
Take Trifluoperazine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Take Trifluoperazine with food. This will help to minimise any stomach discomfort that this medicine may cause. Try to take it at the same time each day.
Trifluoperazine is available as a tablet and oral solution.
If are using the oral solution, use the dropper, measuring spoon or cup provided to measure out your dose accurately.
Trifluoperazine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Trifluoperazine is not suitable for patients with dementia-related psychosis.
Alert your doctor if you have the following conditions:
- liver disease
- blood disorders
- bone marrow suppression
as Trifluoperazine may not be suitable for you.
Inform your doctor if you have the following:
- enlarged prostate
- epilepsy (seizures or fits) or a history of fits
- Parkinson's disease (a brain disease that affects movement)
- glaucoma (increased pressure in the eye)
- heart disease
- kidney disease
- myasthenia gravis (a condition that causes muscle weakness)
- risk factors for stroke
Let your doctor know if you are pregnant or breastfeeding.
If you are going for an operation, including minor operations and dental work, inform your doctor or dentist that you are being treated with Trifluoperazine.
This medicine may affect how your body adjusts to temperature changes. Avoid exposure to very cold or very hot environments.
For as long as you are being treated with Trifluoperazine, you will need to have regular blood tests to make sure that your blood counts are normal. Your doctor will advise you about how often you need to have blood tests.
Trifluoperazine may cause drowsiness, visual disturbance and dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
You may feel dizzy when getting up from a sitting or lying down position, especially if you are taking Trifluoperazine for the first time, or if your doctor is still adjusting your dose. This is normal and should improve gradually as you get used to the medicine. It will help if you get up slowly from a sitting or lying down position.
Other side effects include any of the following: dry mouth, constipation, nausea, vomiting, menstrual irregularities, headache, difficulty sleeping, difficulty urinating, muscle weakness, loss of appetite, weight gain, confusion and water retention.
It may also cause your skin to be more sensitive to sunlight. Apply sunscreen when going outdoors and avoid direct or prolonged exposure to sunlight and UV lamps.
Some side effects may need immediate medical help. Alert your doctor immediately if you experience any of the following:
- fast or irregular heartbeat
- chest pain
- muscle stiffness, unexplained high fever
- uncontrolled muscle movements of your body or face, such as sticking out of the tongue, smacking of the lips
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and your pharmacist if you are taking any of these medicines:
- medicines to treat moderate to severe pain e.g. morphine, fentanyl
- medicines to treat depression e.g. fluoxetine, lithium
- medicines for epilepsy (seizures or fits) e.g. phenytoin, carbamazepine
- medicines to treat Parkinson's disease e.g. levodopa, apomorphine
- medicines to treat irregular heart rate e.g. verapamil, diltiazem
- medicines to treat high blood pressure e.g. guanethidine, propranolol
- medicines used to treat schizophrenia e.g. zotepine
- medicine to treat vomiting called metoclopramide
- blood-thinning medicines such as warfarin
This list does not include all medicines that may interact with Trifluoperazine.
Trifluoperazine must not be taken together with antacids. If you must take antacids, take between meals at least 2 hours after you have taken Trifluoperazine.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
Avoid alcohol. Alcohol will worsen the dizziness and drowsiness caused by Trifluoperazine.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.
If you have been given the oral solution, throw it away 1 month after you open the bottle.