Tripelennamine


Concise Prescribing Info
Indications/Uses
Hypersensitivity reactions.
Dosage/Direction for Use
Adult : PO As HCl: 25-50 mg 4-6 hrly. Max: 600 mg/day.
Dosage Details
Oral
Hypersensitivity reactions
Adult: As hydrochloride: 25-50 mg every 4-6 hr. Max: 600mg daily.
Child: As hydrochloride: 5 mg/kg in 4-6 divided doses daily. Max: 300mg daily.
Contraindications
Neonates.
Special Precautions
Narrow-angle glaucoma, urinary retention, prostatic hypertrophy, pyloroduodenal obstruction, epilepsy. Avoid operating vehicles or machinery. Elderly.
Adverse Reactions
Sedation; CNS depression; antimuscarinic effects; GI disturbances.
Potentially Fatal: Blood dycrasias.
Drug Interactions
Increased sedation with CNS depressants eg, alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytics, sedatives and antipsychotics. Increased antimuscarinic side effects with other antimuscarinic drugs e.g. atropine, TCAs and MAOIs. May mask signs of ototoxicity caused by aminoglycosides.
Lab Interference
May suppress histamine response to allergens and thus may interfere with skin testing.
Action
Description: Tripelennamine is an antihistamine derived from ethylenediamine with antimuscarinic and moderate sedative properties.
Disclaimer: This information is independently developed by MIMS based on Tripelennamine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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