Vaxcel Pantoprazole

Vaxcel Pantoprazole





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Concise Prescribing Info
Short term use for symptomatic improvement & healing of GI diseases which require reduction in acid secretion eg, duodenal & gastric ulcer, moderate & severe reflux esophagitis, Zollinger-Ellison syndrome & other pathological hypersecretory conditions.
Dosage/Direction for Use
40 mg/day IV administered over 2-15 min. Max duration: 8 wk. Long term management of Zollinger-Ellison syndrome & other pathological hypersecretory conditions Initially 80 mg daily. Thereafter, titrate dose up or down as needed. Doses >80 mg: divide dose & give bd.
Hypersensitivity. Co-administration w/ atazanavir.
Special Precautions
Administration is recommended only if oral application is not appropriate. Not indicated for mild GI complaints eg, nervous dyspepsia. Exclude possibility of malignancy of gastric ulcer or disease of esophagus prior to treatment. Renal impairment. Severe liver impairment (discontinue in case of a rise in liver enzymes). Pregnancy & lactation. Elderly. Childn.
Adverse Reactions
Upper abdominal pain, diarrhea, constipation, flatulence; headache.
Drug Interactions
Changes in absorption w/ drugs whose absorption is pH-dependent (eg, ketoconazole). Changes in INR w/ coumarin anticoagulants eg, phenprocoumon or warfarin. Reduced atazanavir bioavailability.
ATC Classification
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Vaxcel Pantoprazole powd for inj 40 mg
10 × 1's
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