Vinorelbine - oral


Patient Medicine Information
Why do I need this medicine?
Vinorelbine is used on its own or together with other medicines to treat certain types of cancer of the lungs and breast.
How do I take this medicine?
Take Vinorelbine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal. Try to take it at the same time each day.

This medicine is available as a capsule. Swallow it whole. Do not chew or suck the capsule.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your condition and response to the medication.

Vinorelbine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • stomach or bowel surgery or gut disorders that affect food absorption
  • severe liver disease
  • low white blood cell counts or a severe infection
  • low platelet count
  • require long term oxygen therapy
as Vinorelbine may not be suitable for you.

DO NOT take this medicine if you are pregnant. If you become pregnant while on Vinorelbine therapy, alert your doctor immediately. This medicine may cause harm to your unborn child.

Men should not father a child while being treated with this medicine. Both men and women must use proven birth control methods during Vinorelbine therapy and for 3 months after stopping the treatment. You may wish to discuss other reliable methods of birth control with your doctor.

DO NOT breastfeed while you are being treated with this medicine.

Alert your doctor if you have been recently vaccinated. You must avoid any vaccinations without first consulting your doctor.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • heart disease e.g. chest pain, heart attack
  • poor performance status (reduced ability to perform or carry out daily living activities)
  • received radiation therapy wherein the treatment field included the liver
Why is it important to keep my appointments with the doctor?

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Pregnancy tests must be done before treatment initiation to know if this medicine is suited for you to take.
  • Routine tests (e.g. blood count, liver function test) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Vinorelbine may cause dizziness and fatigue. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: nausea, vomiting, diarrhoea, mouth sore, loss of appetite, headache, hair loss, difficulty sleeping, changes in your vision.

This medicine may cause the level of your red blood cells, white blood cells and platelets to drop.

Red blood cells carry oxygen around your body. A fall in the level of red blood cells may make you feel tired and worn out.

White blood cells help your body to fight infections. A fall in the level of your white blood cells may put you at higher risk for infections, such as coughs, colds and flu, which may lead to more serious infections. Avoid crowded places and people who are sick. Inform your doctor if you have a fever or a cough or flu that does not go away.

Platelets help your blood to clot when there is a cut in the skin. A fall in the level of your platelets may put you at risk of bleeding more than usual. Do not take part in activities where you may fall or get injured, such as contact sports. Inform your doctor if you get any unusual bruising (large bruises or several bruises, especially if the bruises appeared on their own) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes, breathlessness, swelling of the face, eyes or mouth
  • severe constipation, stomach pain
  • severe chest pain
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • blood-thinning medicine e.g. warfarin, phenindione
  • medicines used to treat fungal infection e.g. itraconazole, ketoconazole
  • phenytoin (medicine for epilepsy) 
  • ritonavir (medicine used for HIV infections)
  • rifampicin (a medicine used for an infection known as tuberculosis)
  • medicines used in organ transplant or certain immune disorders e.g. ciclosporin, tacrolimus
  • other medicines that are used to treat cancer e.g. mitomycin, cisplatin, lapatinib
This list does not include all medicines that may interact with Vinorelbine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8°C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.

Protect from light.

Medicines must not be used past the expiry date.

As this is a cancer medicine, always return any unused or expired capsules to the clinic, hospital, or pharmacy for disposal. Do not throw it away in the household waste.
This information is independently developed by MIMS based on vinorelbine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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