Vismodegib - oral

Patient Medicine Information
Why do I need this medicine?
Vismodegib is used to treat skin cancer.
How do I take this medicine?
Take Vismodegib exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Swallow the capsule whole with a glass of water. Do not open or crush the capsule. Try to take it at the same time each day.

Vismodegib must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.
What should I do if I have forgotten to take this medicine?
If you missed a dose, skip the dose and resume with the next scheduled dose.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Vismodegib if you are pregnant or planning to have a baby soon. If you become pregnant while on Vismodegib, alert your doctor immediately. Vismodegib may cause harm to your unborn child. Both men and women must use two proven birth control methods while being treated with this medicine. You may wish to discuss birth control methods with your doctor. Avoid getting pregnant or avoid fathering a child with your partner during treatment and up to 24 months after you stop taking this medicine.

Do not breastfeed while you are being treated with this medicine and up to 24 months after treatment.
What should I take note of while taking this medicine?
Do not donate blood, blood products or sperm while you are taking Vismodegib and for 24 months (for blood and blood products) or 3 months (for sperm) after your final dose.

Your doctor may need to test you for pregnancy within 7 days before starting treatment and every month during treatment with Vismodegib.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
What side effects could I experience?
Vismodegib may cause any of the following side effects: absence of menstruation, nausea, vomiting, diarrhoea, constipation, stomach pain, decreased appetite, altered taste, weight loss, tiredness, muscle spasm, joint pain, and hair loss.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicine for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin
  • cholesterol-lowering medicines e.g. ezetimibe, atorvastatin, rosuvastatin, simvastatin
  • medicines for diabetes e.g. glibenclamide, repaglinide
  • medicine for tuberculosis or TB e.g. rifampicin
  • medicine for high blood pressure e.g. valsartan
  • medicine for high blood pressure in the blood vessels leading to the lungs e.g. bosentan
  • medicine for certain types of cancer e.g. topotecan
  • herbal medicines e.g. St. John's wort
This list does not include all medicines that may interact with Vismodegib.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on vismodegib - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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