Inflammation, thrombophlebitis, pain at the site of inj. Rash, pruritus, urticaria; rare severe skin reactions eg, erythema multiforme, Stevens-Johnson syndrome & toxic epidermal necrolysis. Abdominal pain, nausea, vomiting, diarrhoea, pseudomembranous colitis. Reversible thrombocythaemia, eosinophilia, thrombocytopenia, leucopenia & neutropenia; +ve direct or indirect Coombs test may develop; reduced partial thromboplastin time. Increased serum conc of bilirubin, transaminases, alkaline phosphatase & lactic dehydrogenase. Headache, paraesthesiae. Oral & vaginal candidiasis.