Zifex Plus

Zifex Plus Dosage/Direction for Use


Zifam Pinnacle


Pinnacle House
Full Prescribing Info
Dosage/Direction for Use
Dosage should be adjusted according to age, body weight and condition of the patients.
Adults: Recommended Dose: One tablet twice daily for 7 days. This may be continued for up to 14 days if required.
Children: Recommended Dose: 8 mg/kg daily as a single dose, or may be in 2 divided doses as 4 mg/kg every 12 hrs. 5 years: 7.5 mL twice daily; 3 years: 6 mL twice daily; 2 years: 5 mL twice daily; 1 year: 4 mL twice daily; 6 months: 2.5 mL twice daily.
>12 years (>50 kg): Same as recommended adult dose.
Renal Impairment: Zifex Plus may be administered in the presence of impaired renal function. Normal dose and schedule may be employed in patients with creatinine clearances of ≥60 mL/min. Patients whose clearance is between 21 and 60 mL/min, or patients who are on renal hemodialysis may be given 75% of the standard dosage at the standard dosing interval (ie, 300 mg daily).
Patients whose clearance is <20 mL/min, or patients who are on continuous ambulatory peritoneal dialysis may be given half the standard dosage at the standard dosing interval (ie, 200 mg daily). Neither hemodialysis nor peritoneal dialysis removes significant amounts of drug from the body.
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