The dose of cefixime should be adjusted in patients with renal impairment as well as those undergoing continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD). Patients on dialysis should be monitored carefully.
Use in pregnancy & lactation: No adequate and well-controlled studies in pregnant women have been reported. Therefore, Zifex Plus should not be used in pregnancy or nursing mothers unless considered essential by the physician.
Use in children: Safety and effectiveness of this combination in children <6 months have not been established.
Neonates: No data are available on the use of the drug in neonates.