Ziglip-M

Ziglip-M

metformin + sitagliptin

Manufacturer:

Zifam Pinnacle

Distributor:

Pinnacle House
Concise Prescribing Info
Contents
Metformin HCl 1,000 mg, sitagliptin phosphate monohydrate 64.25 mg (equiv to sitagliptin 50 mg)
Dosage/Direction for Use
1 tab/day. Individualized to max sitagliptin 100 mg & metformin 2,000 mg.
Contraindications
Diabetic ketoacidosis, diabetic pre-coma; moderate & severe renal impairment (CrCl <60 mL/min). Acute conditions potentially alter renal function (eg, dehydration, severe infection, shock, IV iodinated contrasts). Acute or chronic disease may cause tissue hypoxia (eg, cardiac or respiratory failure). Hepatic impairment; acute alcohol intoxication, alcoholism. Lactation.
Special Precautions
Patients w/ Type 1 DM or for diabetic ketoacidosis. Determine serum CrCl regularly; increased incidence of metformin-related lactic acidosis w/ degree of renal impairment. Potential risk for hypoglycaemia w/ sulphonylurea or insulin combination. Pancreatitis. Pregnancy.
Drug Interactions
Minimal effect on plasma digoxin conc w/ sitagliptin.
MIMS Class
ATC Classification
A10BD07 - metformin and sitagliptin ; Belongs to the class of combinations of oral blood glucose lowering drugs. Used in the treatment of diabetes.
Presentation/Packing
Form
Ziglip-M FC tab
Packing/Price
1 × 10's;10 × 10's;100's;3 × 10's;30's
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