Onasemnogene abeparvovec commonly linked to hepatotoxicity
27 Feb 2021
Hepatotoxicity is common after treatment with onasemnogene abeparvovec for spinal muscular atrophy, a recent study has found. Clinicians should anticipate and be ready to manage such adverse events, and be aware of any potential underlying conditions that could aggravate them.
Optimizing metastatic hormone-sensitive prostate cancer treatment in advanced prostate cancer
14 Jan 2021;
Metastatic hormone-sensitive prostate cancer (mHSPC) refers to the condition whereby patients have metastatic prostate cancer and no prior hormonal therapy or androgen deprivation therapy (ADT). Typically, patients with mHSPC have been treated with ADT alone, following which, the overwhelming majority develop castration resistance over time and head towards eventual mortality. In recent years, the publication of various landmark trials has prompted dramatic changes in the mHSPC treatment landscape, and had favourably impacted overall survival (OS) in these patients. At a recent webinar, A/Prof Darren Poon, Honorary Consultant in Clinical Oncology, Hong Kong Sanatorium & Hospital, and Honorary Clinical Associate Professor, Department of Clinical Oncology, The Chinese University of Hong Kong, reviewed treatment options in mHSPC, while A/Prof Edmund Chiong, Head and Senior Consultant, Department of Urology, National University Hospital, Singapore, presented a case which was discussed by an esteemed panel of experts. This webinar was jointly organized by the Singapore Society of Oncology and the Singapore Urological Association, and supported by Astellas.
Contents : Sultamicillin (ampicillin & sulbactam). Per tab Sultamicillin tosylate 750 mg. Per 375 mg vial Ampicillin 250 mg, sulbactam 125 mg. Per 750 mg vial Ampicillin 500 mg, sulbactam 250 mg. Per 1.5 g vial Ampicillin 1 g, sulbactam 500 mg
Indications/Uses : Tab: Treatment of infections where β-lactamase-producing organisms might occur including uncomplicated gonorrhea, otitis media, resp tract infections & UTI. Inj: Treatment of upper & lower resp tract & gynecological infections. Prophylaxis to reduce the risk of infections following surgery or caesarean section during birth.
Indications/Uses : Advanced prostate cancer in combination w/ luteinizing hormone-releasing hormone (LHRH) analogue therapy or surgical castration. Monotherapy or as adjuvant to radical prostatectomy or radiotherapy in patients w/ locally advanced prostate cancer at high risk for disease progression.
Indications/Uses : Fortification Shampoo Nourish & repairs the hair fiber. Fortification Intensive Lotion Fights the ageing process & stimulates hair microcirculation, reinforcing the weakened structure. Helps give body to the hair & stimulates the activity of the bulbs. Fortification Intensive Lotion Plus Helps slow down the hair fall & stimulates new hair formation by stimulating the blood circulation in the capillaries. Repairs weak structures. Helps your hair look thicker. Stimulates the activity of the hair bulb.
Indications/Uses : Complementary symptomatic treatment of acute diarrhea in infants (>3 mth) & in childn together w/ oral rehydration & usual support measures, when measures alone are insufficient to control & when causal treatment is not possible. As complementary treatment if causal treatment is possible.
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