Acifre

Acifre

omeprazole

Manufacturer:

GXI

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Omeprazole
Indications/Uses
Gastric acid reduction; aspiration syndromes, dyspepsia, GERD, PUD & Zollinger-Ellison syndrome. NSAID associated ulcer.
Dosage/Direction for Use
GERD 20 mg once daily for 4 wk. Dyspepsia 10-20 mg daily for 2-4 wk. PUD 20 mg daily as single dose or 40 mg in severe cases. NSAID-associated ulceration 20 mg daily. Zollinger-Ellison syndrome 60 mg once daily. Acid aspiration prophylaxis during general anesth 40 mg in the evening before surgery & further 40 mg 2-6 hr before the procedure.
Administration
Should be taken with food: Take immediately before a meal.
Contraindications
Special Precautions
Consider possibility of malignancy prior to treatment in patients w/ gastric ulcers. Hepatic impairment.
Adverse Reactions
Headache, diarrhea & skin rash. Pruritus, dizziness, fatigue, constipation, nausea & vomiting; flatulence, abdominal pain; arthralgia & myalgia; urticaria & dry mouth. Increase risk of GI infection due to acid suppressive effect.
Drug Interactions
May increase GI pH & reduced absorption of ampicillin esters, Fe salts or ketoconazole. Decrease in hepatic metabolism, delayed elimination & increase blood conc of anticoagulants (coumarin or indandione-derivative), diazepam or phenytoin. Increase leukopenic &/or thrombocytopenic effects w/ bone marrow depressants.
ATC Classification
A02BC01 - omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Acifre cap 20 mg
Packing/Price
50's (P20.4/cap)
Form
Acifre cap 40 mg
Packing/Price
24's (P36.3/cap)
Form
Acifre powd for inj 40 mg
Packing/Price
(+ 10 mL amp diluent) 10 mL x 1's (P480/box)
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