Actimed Celecoxib

Actimed Celecoxib

celecoxib

Manufacturer:

Endurance

Distributor:

Actimed

Marketer:

Ambica
Concise Prescribing Info
Contents
Celecoxib
Indications/Uses
RA, OA & ankylosing spondylitis. Adjunctive treatment of adenomatous colorectal polyps. Management of acute pain & dysmenorrhea.
Dosage/Direction for Use
OA 200 mg daily as single or in 2 divided doses, may be increased to 200 mg bid if necessary. RA 100-200 mg bid. Ankylosing spondylitis Initially 200 mg daily as single or in 2 divided doses, may be increased to 400 mg daily after 6 wk if necessary. Pain & dysmenorrhea Initially 400 mg followed by an additional dose of 200 mg if necessary on the 1st day, thereafter 200 mg bid. Adjunct to standard therapy in reducing number of adenomatous colorectal polyps in patient w/ familial adenomatous polyposis (FAP) 400 mg bid.
Administration
May be taken with or without food: Dose for OA/RA may be given w/ or w/o meals, but doses for adenomatous colorectal polyps must be given w/ meals.
Contraindications
Hypersensitivity. Peri-operative pain in the setting of CABG surgery. Not to be given in patients w/ allergy to NSAIDs, asthma.
Special Precautions
Increased risk of serious CV thrombotic event, MI & stroke. Increased risk of GI events including bleeding, ulceration & perforation of the stomach or intestines. Patients w/ allergy to NSAIDs & those w/ asthma. Ischemic heart disease, risk factors for heart disease, HTN, hyperlipidemia, diabetes, peripheral arterial disease; smoking; cerebrovascular disease. Significant risk factors for CV disease or peripheral arterial disease. Dehydrated patients. Discontinue use w/ appearance of skin rash & signs of hypersensitivity. Elderly.
Adverse Reactions
GI disturbances especially diarrhea; exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis; anaphylaxis; angioedema.
Drug Interactions
Decreased absorption by antacids or histamine H2-receptor antagonists. Reduced renal excretion w/ probenecid.
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Presentation/Packing
Form
Actimed Celecoxib cap 200 mg
Packing/Price
100's
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