Diclofenac Spray is usually well tolerated.
Occasional: allergic or non-allergic contact dermatitis (with symptoms and signs such as itching, reddening, edema, papules, vesicles, bullae or scaling of skin).
Hypersensitivity reactions have been reported following treatment with NSAIDs. These may consist of (a) non-specific allergic reaction and anaphylaxis, (b) respiratory tract reactivity comprising asthma, aggravated asthma, bronchospasm or dyspnea or (c) assorted skin disorders including rashes of various types, pruritus, urticaria, purpura, angioedema, and less commonly, bullous dermatoses (including epidermal necrolysis, erythema multiforme and exfoliative dermatitis.
Patients should be warned against excessive exposure to sunlight in order to reduce the incidence of photosensitivity.
Systemic absorption of Diclofenac Spray is low compared with plasma levels obtained following administration of oral forms of Diclofenac and the likelihood of systemic side-effects occurring with topical Diclofenac is small compared with the frequency of side-effects associated with oral Diclofenac. However, where Diclofenac Spray is applied to a relatively large area of skin and over a prolonged period, the possibility of systemic side-effects cannot be completely excluded. If such usage is envisaged, the data sheet on Diclofenac oral dosage forms should be consulted.
Abdominal pain, dyspepsia.
Bronchospasms may be precipitated in patients suffering from or with a previous history of asthma or allergic disease.