Cetirizine hydrochloride should be used with caution in patients who requires mental alertness of physical coordination in their work such as drivers or machine operators since it may cause drowsiness.
Use in Children: Infants and children must not be given Cetirizine hydrochloride as this may increase risk of experiencing antimuscarinic effects.
Use in Elderly: Cetirizine hydrochloride must be used with caution in elderly patients who most likely have impaired renal and hepatic function. Since the drug is metabolized through the renal mechanism, half life of Cetirizine hydrochloride in such patients will be prolonged. Dose of the drug must be reduced in elderly patients.
Use in Pregnancy: No data is available on the safety of administration of Cetirizine hydrochloride in pregnant women apart from an animal study which reveals absence of teratogenicity. As such, Cetirizine hydrochloride must be given to pregnant patients only when necessary.
Use in Lactation: Cetirizine hydrochloride is excreted in breast milk. Thus use in lactating mothers is not recommended.