Airex

Airex

cefalexin

Manufacturer:

Medhaus

Distributor:

Medhaus
Full Prescribing Info
Contents
Cefalexin monohydrate.
Description
Each capsule contains: Cefalexin (as Monohydrate) 250 mg and 500 mg.
Each 5 mL (1 teaspoonful) contains: Cefalexin (as Monohydrate)125 mg.
Each 5 mL (1 teaspoonful) contains: Cefalexin (as Monohydrate) 250 mg.
Each mL contains: Cefalexin (as Monohydrate) 100 mg.
Action
Pharmacology: Pharmacokinetics: Absorption: Cefalexin is acid stable and is readily absorbed after oral administration, food may delay absorption. Intramuscular doses of the lysine salt are well absorbed up to 15% of a dose is bound to plasma proteins. The half-life had been reported to range from 0.5 to 2.0 hours and this increase with reduced renal function. Cefalexin is widely distributed in the body does not enter cerebrospinal fluid significant quantities. It diffuses across the placenta and small quantities are found in the milk or nursing mothers. About 80% or more of a dose is excreted unchanged in the urine in the first 6 hours by glomerular filtration and tubular secretion. Probenecid delays urinary tract excretion and has been reported to increase biliary excretion.
Indications/Uses
For the treatment of urinary tract infection and respiratory tract infection, otitis media, skin and other infections due to sensitive organisms.
Dosage/Direction for Use
Adult: 1-2 g daily given in divided doses at 6-8 or 12 hourly intervals.
For severe or deep-seated infections: can be increased to up to 6 g daily.
Children: 25 to 100 mg per Kg body weight daily in divided doses to maximum of 4 g/grams daily.
For prophylaxis of recurrent urinary-tract-infection: 250 mg at night.
Or as prescribed by the physician.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
It should be used with caution in allergic patients, especially when there is history of penicillin allergy. Reduced dosage is recommended in patients with severe renal impairment.
Adverse Reactions
Cefalexin may cause abdominal discomfort and diarrhea in some patients, allergic reactions, such as skin rashes, urticarial, eosinophilia, angioedema and anaphylaxis may occur and rises in liver enzyme value have been noted.
Drug Interactions
Bacteriostatic antibiotics, Probenecid.
Caution For Usage
Direction For Reconstitution: 100 mg/mL Powder for Suspension (Oral Drops): To make 10 mL reconstituted suspension, mix thoroughly with 8 mL and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30°C and 14 days under refrigeration (2-8°C).
125 mg/5 mL Powder for Suspension: To make 60 mL reconstituted suspension, mix thoroughly the contents with 42 mL water and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30°C and 14 days under refrigeration (2-8°C).
250 mg/5 mL Granules for Suspension: To make 60 mL reconstituted suspension, mix thoroughly the contents with 43 mL water and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30°C and 14 days under refrigeration (2-8°C).
Storage
Store at temperature not exceeding 30°C.
MIMS Class
Cephalosporins
ATC Classification
J01DB01 - cefalexin ; Belongs to the class of first-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Cap 250 mg x 100's. 500 mg x 50's. Oral susp 125 mg/5 mL x 60 mL. 250 mg/5 mL x 60 mL. Oral drops 100 mg/mL x 10 mL.
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in