Alnix Plus Syrup

Alnix Plus Syrup

Manufacturer:

Amherst Lab

Distributor:

Pediatrica
Full Prescribing Info
Contents
Cetirizine dihydrochloride, phenylephrine hydrochloride.
Description
Each 5 mL (1 teaspoonful) syrup contains: Cetirizine dihydrochloride 5 mg and Phenylephrine HCl 5 mg.
TasteRite technology is a unique tastemasking system developed specifically for liquid dosage forms. This technology significantly reduces the bitterness of medicine so that children taste the flavor and not the medicine.
Action
This medicine contains cetirizine and phenylephrine HCI. Cetirizine, an antiallergy, blocks the action of histamine, a substance that causes allergic symptoms. Cetirizine is less likely to cause drowsiness and dizziness than the older class of anti-allergy medicines. Phenylephrine HCI, a nasal decongestant, clears obstructed air passages and nasal sinuses due to congestion making breathing easier. It also reduces postnasal drip.
Indications/Uses
This medicine is used for the relief of clogged nose; sneezing; runny, itchy nose; and itchy, watery eyes associated with allergic rhinitis.
Dosage/Direction for Use
This medicine should be taken orally (by mouth) every 12 hours, or, as directed by a doctor.
Children: 2 to 5 years: 2.5 mL (½ teaspoonful).
6 to 12 years: 5 mL (1 teaspoonful).
Missed Dose: If the patient misses a dose, just give the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e., every 12 hours).
Do not double the dose.
Overdosage
Symptoms of Cetirizine overdose include sleepiness, drowsiness, restlessness, and irritability.
Phenylephrine HCl overdose is usually associated with tiredness, sweating, dizziness, slow heart beat, and coma.
If the patient has taken more than the recommended dosage, consult a doctor.
Contraindications
Do not give this medicine if the patient: Is allergic to any ingredient in the product.
Is taking medicines for depression.
Has high blood pressure or severe heart disease.
Special Precautions
This medicine should be given with care to patients with kidney or liver disease including patients taking other drugs that affect the liver.
Consult a doctor: Before giving this medicine, tell the doctor if the patient has: High blood pressure or any type of heart problems; Glaucoma; Thyroid problems; Diabetes; Liver or kidney disease; Bladder problems or difficulty urinating.
If symptoms do not improve or new symptoms occur.
Adverse Reactions
Cetirizine: The most common undesirable effects of Cetirizine include headache, drowsiness/sleepiness, dry mouth, sore throat, coughing, bronchospasm (sudden, uncontrolled narrowing of airways in lungs), epistaxis (nose bleeding), stomach pain, diarrhea, nausea, and vomiting.
The following rare events have been reported but it is not known whether they are directly related to Cetirizine use.
Nervous System: Ataxia (uncontrolled muscle movement, incoordination), confusion, abnormal thinking, agitation, amnesia, anxiety, convulsions, depersonalization (alteration in the perception of the self so that the usual sense of one's own reality is lost), depression, dysphonia (difficulty in speaking), emotional lability (emotional instability), euphoria (an exaggerated unrealistic sense of well-being), impaired concentration, insomnia/sleep disorders, nervousness, hyperesthesia (increased sensitivity to any stimulation), hypoesthesia (abnormally decreased sensitivity), hyperkinesia (hyperactivity), hypertonia (muscle stiffness), migraine, myelitis (inflammation of the spinal cord), paralysis, paresthesia (abnormal sensation, such as burning, prickling, or tingling), ptosis (drooping of eyelids), syncope (fainting/temporary loss of consciousness), tremor, twitching, vertigo.
Cardiovascular: Palpitation, tachycardia (rapid heart rate), increased blood pressure, chest pain, heart failure, rarely decreased blood pressure.
Respiratory: Bronchitis, dyspnea (shortness of breath), hyperventilation (rapid breathing), increased sputum, pneumonia, respiratory disorder, rhinitis, sinusitis, upper respiratory tract infection.
Gastrointestinal: Anorexia (loss of appetite), increased appetite, increased salivation, tongue discoloration, swelling of tongue, tooth caries, taste loss, taste perversion, dyspepsia, gastritis, stomatitis/ulcerative stomatitis (sores in the mouth), enlarged abdomen, eructation (burping), flatulence (gassiness), constipation, melena (black stools caused by bleeding in the stomach or small intestine), rectal bleeding, hemorrhoids.
Genitourinary and Renal: Cystitis (inflammation of the urinary bladder), dysuria (painful urination), hematuria (blood in the urine), polyuria (excessive urination/frequent urination), urinary incontinence (inability to control urination), urinary retention (difficulty urinating), urinary tract infection, glomerulonephritis (inflammation of the kidney).
Reproductive: Dysmenorrhea, intermenstrual bleeding (bleeding between two menstrual periods), female breast pain, leucorrhea (whitish vaginal discharge), menorrhagia (heavy menstrual bleeding), decreased libido, vaginitis (inflammation of the vagina).
Hepatic: Hepatitis and increased liver enzymes (e.g, aminotransferases, bilirubin).
Ocular (Eye) and Otic (Ear): Visual problems, blindness, conjunctivitis (irritation and redness of the thin membrane covering the eye), eye pain, glaucoma, loss of eye accommodation, eye bleeding, periorbital edema (accumulation of fluid surrounding the socket of the eye), xerophthalmia (dry eye), deafness, otalgia (earache), ototoxicity (toxicity to the ears), tinnitus (ringing in the ears).
Skin: Acne, alopecia (baldness), angioedema (rapid swelling of the skin), bullous eruption (large blisters), dermatitis (skin inflammation), dry skin, eczema, furunculosis (boils), hyperkeratosis (thickened skin), hypertrichosis (excessive hair growth), increased sweating, light sensitivity, pruritus (itchiness), purpura (small purple-red marks in skin), urticaria/rash, seborrhea, skin disorder, skin nodule.
Musculoskeletal: Arthralgia (joint pain), arthritis, arthrosis/osteoporosis, muscle weakness, myalgia (muscle aches), asthenia (weakness), malaise (feeling of bodily discomfort), leg cramps.
Other undesirable effects: Anaphylaxis (rare, life-threatening allergic reaction), back pain, cholestasis (inflammation of the gall bladder), dehydration, diabetes mellitus, swelling (generalized, facial, leg, or peripheral), fever, increased weight, lymphadenopathy (swelling of the lymph nodes), pallor, rigors (shaking), hemolytic anemia (anemia resulting from destruction of red blood cells), thrombocytopenia (decreased number of platelets), parosmia (distorted sense of smell), thirst.
Phenylephrine HCl: The most common undesirable effects of Phenylephrine are tremor (muscle shaking), restlessness, anxiety (feeling of uneasiness), nervousness, dizziness, high blood pressure, rapid and irregular pulse, weakness, nausea, vomiting, and sweating.
Drug Interactions
Do not use this product together with sympathomimetic agents (e.g., Epinephrine, etc.) and general anesthetics (e.g., Halothane, etc.) because of the possibility for increased toxicity.
Concurrent administration with medicines for depression (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide, etc.) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of this product may decrease the effect of Phenylephrine.
Tell the doctor about other medicines the patient is taking, especially other medicines for cough, cold or allergy.
Storage
Store at temperatures not exceeding 30°C.
ATC Classification
R01BA53 - phenylephrine, combinations ; Belongs to the class of systemic sympathomimetic preparations used as nasal decongestants.
Presentation/Packing
Syr (clear syrup with fruity grape odor, and sweet grape taste using the TasteRite Technology) 60 mL.
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