Amara/Amara-4

Amara/Amara-4

glimepiride

Manufacturer:

Synmedic

Distributor:

Corbridge

Marketer:

Ambica
Concise Prescribing Info
Contents
Glimepiride
Indications/Uses
Type 2 DM when diet, physical exercise & wt reduction alone are inadequate.
Dosage/Direction for Use
1-2 mg daily. May be increased to 4 mg daily for maintenance.
Administration
Should be taken with food: Take immediately before or during breakfast, or the 1st main meal of the day. Do not skip meals.
Contraindications
Hypersensitivity to glimepiride, other sulfonylureas or sulfonamides. Insulin dependent (type I) DM (eg, diabetics w/ history of ketoacidosis) or diabetic precoma or coma. Amara-4 Severe renal or hepatic function disorders.
Special Precautions
Not to be used for type 1 DM. Hypoglycemia. May lead to hemolytic anemia in patients w/ G6PD deficiency. Regular monitoring of glucose levels in blood & urine. Impaired renal function. Severe impairment of liver function. Pregnancy & lactation. Amara May affect ability to operate a vehicle or heavy machinery. Amara-4 Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Require regular hepatic & hematological monitoring. Temporary switch to insulin in stress situations (eg, accidents, acute operations, infections w/ fever).
Adverse Reactions
Amara Hypoglycemia, temporary visual impairment, GI disturbances. Amara-4 GI disturbances eg, nausea, vomiting, heartburn, anorexia & diarrhea. Increased appetite & wt gain; skin rashes, pruritus & photosensitivity.
Drug Interactions
Increased hypoglycemic effect w/ chloramphenicol, coumarin anticoagulants, sulphonamides, salicylates & thyroid hormones. Amara Increased hypoglycemic effect w/ ACE inhibitors, alcohol, allopurinol some analgesics (eg, azapropazone, phenylbutazone), azoles (eg, fluconazole, ketoconazole & miconazole), cimetidine, clofibrate & related compds, halofenate, heparin, MAOIs, octreotide, ranitidine, sulphinpyrazone, tetracyclines, TCAs. Amara-4 May potentiate hypoglycemic action w/ NSAIDs & probenecid. May produce hyperglycemic w/ thiazides, other diuretic, phenothiazines, OCs & phenytoin.
MIMS Class
ATC Classification
A10BB12 - glimepiride ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.
Presentation/Packing
Form
Amara-4 tab 4 mg
Packing/Price
100's
Form
Amara tab 2 mg
Packing/Price
30's
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