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Amara: Hypersensitivity to Glimepiride, other sulfonylureas, other sulfonamides or any of the excipients. Insulin dependent (type I) diabetes mellitus (e.g., for the treatment of diabetics with a history of ketoacidosis) or diabetic precoma or coma.
Amara-4: Glimepiride is contraindicated in patients with the following conditions: hypersensitivity to glimepiride, other sulfonylureas or sulfonamides or to any of the excipients; insulin dependent diabetes; diabetic coma; ketoacidosis; severe renal or hepatic function disorders.
In case of severe renal or hepatic function disorders, a change over to insulin is required.
