Amiabel Dosage/Direction for Use





United Lab
Full Prescribing Info
Dosage/Direction for Use
Doses should preferably be given before meals.
Amisulpride should be administered twice a day for doses above 400 mg.
Doses should be adjusted based on individual patient response.
There is no specific titration required when initiating treatment with amisulpride.
Maintenance treatment should be established individually with the minimally effective dose.
Recommended Adult Oral Amisulpride Dose: For acute psychotic episodes: Oral doses between 400 mg and 800 mg per day; In individual cases, the daily dose may be increased up to 1,200 mg per day.
Doses above 1,200 mg per day have not been evaluated for safety and should not be used.
For patients with mixed positive and negative symptoms: Initially, 400 mg to 800 mg per day; Doses should then be adjusted to obtain optimal control of positive symptoms.
For patients with predominant negative symptoms: Oral doses between 50 mg and 300 mg per day.
Special Population: Renal Insufficiency: Dose should be reduced to half in patients with creatinine clearance (CLCr) between 30 to 60 mL/min and to a third in patients with CLCr between 10 to 30 mL/min.
As there is no experience in patient with severe renal impairment (CLCr < 10 mL/min), particular care is recommended in these patients.
Hepatic Impairment: Dose reduction is not necessary since amisulpride is weakly metabolized.
Or, as prescribed by a physician
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