Amiloride is used to treat water retention caused by heart failure, liver or kidney disease. Water retention may be noticed as swelling of the feet, ankles, lower leg and hands or shortness of breath. For this reason, it is commonly known as a "water pill".
Amiloride is also used to treat high blood pressure.
Take Amiloride exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Take Amiloride with a meal. This will help to minimise any stomach discomfort that may occur. Try to take it at the same time each day.
You will feel the urge to pass urine more often while being treated with Amiloride. Take it early in the day, preferably in the morning, to avoid waking up frequently at night to go to the toilet.
Amiloride must be taken regularly for it to work well. Continue taking Amiloride even when you feel better. Do not stop taking it unless instructed by your doctor.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you:
- have kidney disease
- have high potassium levels
- are taking any other types of "water pills" such as spironolactone or potassium supplements
as Amiloride may not be suitable for you.
Inform your doctor if you have the following conditions:
- liver disease
Let your doctor know if you are pregnant or breastfeeding.
If you are going for an operation, including minor surgery and dental work, inform your doctor, surgeon or dentist that you are taking Amiloride.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medicine regularly. He may also need to do routine blood tests while you are being treated with Amiloride.
What lifestyle changes can I make to improve my blood pressure?
Regular exercise and eating a healthy diet will help lower your blood pressure and improve your overall health. Engage in physical activity (e.g. walking) at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.
If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to kick your smoking habit.
Amiloride may cause weakness or dizziness. If affected, do not drive or take part in any activity in which you need to be alert. You may feel dizzy when getting up from a sitting or lying down position, especially if you are taking Amiloride for the first time. This is normal and should go away as you get used to the medicine. It will help if you get up slowly.
You may need to pass urine more often while you are being treated with Amiloride. As your body adjusts to the medicine, this urination effect should also decrease.
Amiloride may also cause any of the following side effects: nausea, vomiting, loss of appetite, stomach wind, dry mouth, stomach discomfort, headache, tiredness and rashes.
Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:
- fast or irregular heartbeat
- muscle weakness, cramping or numbness
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for heart disease or high blood pressure e.g. enalapril, losartan, digoxin, quinidine
- other similar types of medicine e.g. spironolactone, eplerenone
- NSAIDs (medicines for pain and inflammation) e.g. ibuprofen
- lithium (medicine for mood)
- ciclosporin or tacrolimus (medicines used in organ transplant or certain immune disorders)
This list does not include all medicines that may interact with Amiloride.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
Do not take potassium supplements. Avoid taking too much food that is high in potassium, such as orange juice, bananas or prunes. Do not use salt substitutes that contain potassium.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.