Amlodine Plus Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

5 mg/50 mg Amlodipine besilate 5 mg, losartan K 50 mg. 5 mg/100 mg Amlodipine besilate 5 mg, losartan K 100 mg

Indications/Uses

Mild to moderate HTN in case of inadequate control w/ monotherapy.

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Dosage/Direction for Use

Stable & Prinzmetal's angina Initially 1 tab once daily. Increase to 2 tab daily if necessary.

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Cardiogenic shock, recent MI, acute unstable angina & chronic stable angina attack. Pregnancy.

Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Amlodine Plus detailed prescribing information

Special Precautions

Patients w/ hypotension, poor cardiac reserve, heart failure, vol depletion; severe aortic stenosis; hepatic & renal impairment; renal artery stenosis. Sudden w/drawal may exacerbate angina. Discontinue if ischemic pain following administration occurs. Monitor serum K conc. Avoid concomitant use w/ K-sparing diuretics. Hepatic & renal impairment. Lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Dizziness, flushing, headache, hypotension, peripheral edema, tachycardia, palpitations. Nausea, GI disturbances, increased micturition frequency, lethargy, eye pain, mental depression. Paradoxical increase in ischemic chest pain at the start of treatment. Rashes, fever, abnormalities in liver function (cholestasis), hyperplasia, myalgia, tremor, impotence.

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Drug Interactions

May enhance antihypertensive effects of other antihypertensives eg, β-blockers, aldesleukin, antipsychotics, quinidine, carbamazepine, phenytoin, rifampicin, cimetidine & erythromycin.

Storage

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Description

View Amlodine Plus description for details of the chemical structure and excipients (inactive components).

Action

View Amlodine Plus mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Angiotensin II Antagonists / Calcium Antagonists / Anti-Anginal Drugs

ATC Classification

C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Amlodine Plus 5 mg/100 mg FC tab

Packing/Price

30's (P817.5/box)

Form

Amlodine Plus 5 mg/50 mg FC tab

Packing/Price

30's (P557.5/box)

Amlodine Plus

Manufacturer:

InnoGen Pharmaceuticals

Distributor:

InnoGen Pharmaceuticals