Body as a Whole: Asthenia, malaise, pain, fatigue.
Nervous System: Hypertonia, hypoesthesia, paresthesia, peripheral neuropathy, tremor, insomnia, mood changes, somnolence, dizziness, headache, vertigo, nervousness, depression, abnormal dreams, anxiety, depersonalization.
Cardiovascular: Hypotension, syncope, vasculitis, palpitations, myocardial infarction, arrhythmia (including ventricular tachycardia and atrial fibrillation), tachycardia, flushing, edema, chest pain, peripheral ischemia, postural dizziness, postural hypotension.
Gastrointestinal: Dry mouth, thirst, altered bowel habits, dyspepsia, gastritis, gingival hyperplasia, pacreatitis, nausea, vomiting, abdominal pain, constipation, dysphagia, diarrhea, flatulence.
Endocrine/Metabolic: Gynecomastia, hyperglycemia, impotence, increased/decreased weight, anorexia.
Hematological: Purpura, thrombocytopenia, leukopenia.
Skin and Appendages: Increased sweating, alopecia, skin discoloration, urticaria, allergic reactions including pruritus, rash, angioedema, and erythema multiforme, purpura.
Urogenital/Reproductive: Increased urinary frequency, micturition disorder, nocturia.
Hepatic: Hepatitis, jaundice, hepatic enzyme elevations.
Musculoskeletal: Arthralgia, arthrosis, muscle cramps, myalgia, back pain.
Respiratory: Coughing, dyspnea, rhinitis, epistaxis.
Special Senses: Taste perversion, tinnitus, visual disturbances, abnormal vision, conjunctivitis, diplopia, eye pain.
Body as a Whole: Fever, fatigue, weakness.
Nervous System: Insomnia, cephalalgia, dizziness, restlessness, vertigo, paresthesia, headache.
Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics, antihypertensive drugs), transient cerebral ischemic attacks.
Gastrointestinal: Sialadenitis, spasms, stomach irritation, nausea, vomiting, diarrhea, constipation, pancreatitis, cramping, gastric irritation.
Endocrine/Metabolic: Anorexia, hyperglycemia, hyperuricemia, hypokalemia, hyponatremia, hypochloremic alkalosis, hypophosphatemia, hypomagnesemia, hypercalcemia, glucose tolerance impairment, glycosuria, increased total cholesterol, low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c) and triglycerides, impotence.
Hematologic: Agranulocytosis, aplastic anemia, hemolytic anemia, leukopenia, thrombocytopenia.
Skin and Appendages: Rash, erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia, anaphylactic reaction, necrotizing angiitis (vasculitis, cutaneous vasculitis), purpura, urticaria, photosensitivity, polyarteritis nodosa.
Urogenital/Reproductive: Glycosuria, interstitial nephritis, renal dysfunction, failure and impairment.
Hepatic: Icterus (intrahepatic cholestatic jaundice).
Musculoskeletal: Muscle cramps and spasm.
Respiratory: Respiratory distress including pneumonitis and pulmonary edema.
Special Senses: Transient blurred vision, xanthopsia.