Anazo

Anazo

anastrozole

Manufacturer:

TTY Biopharm

Distributor:

American Taiwan Biopharma
Concise Prescribing Info
Contents
Anastrozole
Indications/Uses
Adjuvant treatment of postmenopausal women w/ estrogen receptor +ve early invasive breast cancer. 1st-line treatment of postmenopausal women w/ estrogen receptor +ve or estrogen receptor unknown locally advanced or metastatic breast cancer. Advanced breast cancer in postmenopausal women w/ estrogen receptor -ve & previous +ve clinical response to tamoxifen.
Dosage/Direction for Use
Adult & elderly 1 mg tab once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Premenopausal women. Estrogen-containing therapies & tamoxifen. Severe renal impairment (CrCl <20 mL/min). Moderate to severe hepatic impairment. Pregnancy & lactation.
Special Precautions
Women w/ or at risk of osteoporosis. Formally assess bone mineral density by bone densitometry eg, DEXA scanning at the commencement of treatment & at regular intervals thereafter. Concomitant use w/ LHRH analogues. Recommended duration of treatment for early disease. May affect driving or operating machinery as asthenia & somnolence may occur. Not recommended use for childn.
Adverse Reactions
Hot flushes. Asthenia; joint pain/stiffness; vag dryness; hair thinning, rash; nausea, diarrhea; headache.
Drug Interactions
May diminish pharmacologic action w/ estrogen-containing therapies & tamoxifen.
ATC Classification
L02BG03 - anastrozole ; Belongs to the class of enzyme inhibitors. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Anazo tab 1 mg
Packing/Price
28's
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