GERD, erosive esophagitis
20-40 mg once daily for 4 wk, increased to 8 wk if necessary; 16 wk for erosive esophagitis. Maintenance: Continue w/ 20-40 mg daily. Alternatively, for recurring symptoms, 20 mg daily may be given. PUD
40 mg once daily for 2-4 wk (for duodenal ulcer) or 4-8 wk (for benign gastric ulcer). Prophylaxis for NSAID-associated ulceration
20 mg daily. Zollinger-Ellison syndrome
Initially 80 mg daily up to 240 mg daily. Doses >80 mg should be given in 2 divided doses.